Albright’s syndrome

Below you will find more information about Albright’s syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Albright’s syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Albright’s syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Albright’s syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


In 1937, Donovan James McCune and Fuller Albright explained Albright's syndrome as an inherited condition distinguished by abnormalities in the skin pigmentation, bone ailments and endocrine complications. The diseases in the bone may result to the weakness of the bone and abnormalities in the legs, arms and skull. Diseases in the endocrine may the reason for early puberty and elevated growth rate. Patients are affected by several distinctiveness of the ailment to various degrees several individuals may have the condition and have no evident complications.


1) Bone treatments a) Surgical bone grafting b) Surgical bone pinning c) Surgical bone casting 2) Ovary surgery a) Surgical ovary cyst removal b) Ovary removal 3) Estrogen inhibitors a) Testolactone - artificial androgen with antineoplastic movement. Prevents the development of estrogen from adrenal androstenedione and reducing endogenous estrogen levels because it inhibits steroid aromatase. b) Fadrozole 4) Thyroid-inhibiting medications a) Propylthiouracil b) Methimazole 5) Pituitary-related treatments a) Pituitary surgery b) Somatostatin medications 6) Treatments for phosphorus problems a) Oral phosphates b) Vitamin D

Symptoms and Signs

It is supposed that when two of the three subsequent features are evident: (autonomous) endocrine hyperfunction such as precocious puberty Fibrous dysplasia Caf╬ś-au-lait spots


LH blood test FSH blood test Phosphate urine test Ultrasonography X-ray - for bone disease

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