Angular Cheilitis

Below you will find more information about Angular Cheilitis from Medigest. If you believe that you are suffering from any of the symptoms of Angular Cheilitis it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Angular Cheilitis and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Angular Cheilitis comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


A chronic inflammatory condition of the corners of the mouth is called angular cheilitis or perleche. It is usually associated with a bacterial (Staphylococcal) or fungal (Candidal) infection, and those infected may also have thrush (an oral candidiasis). Depending upon whether or not the affected person seeks treatment, the condition can last from days to months.


A dentist or a doctor can diagnose angular cheilitis in different ways, depending on what causes the disease. The problem can also be diagnosed by your dentist by judging the fit of your dentures.


Clotrimazole, nystatin and econazole are topical antifungals which are usually undertaken for the treatment of angular cheilitis. What may also be prescribed are combinations of a topical antifungal and a topical steroid such as mycostatin, hydrocortisone and triamcinolone or iodoquinol.

Symptoms and Signs

Found in the corners of the mouth, a patient with angular cheilitis may notice ulceration, tissue softness and tenderness, cracking and fissuring of the corners of the mouth, with redness and as well as drainage of pus.


Among the variety of reasons why angular cheilitis occurs are from bacterial (Staphylococcal) or viral infections and as well as fungal (Candidiasis) or yeast infection. Those who are taking the isotretinoin medication for acne are more vulnerable to angular cheilitis caused by bacterial and fungal infections. Dentures that are worn and do not fit properly can also be a cause for angular cheilitis because of the friction and folds being created. Deficiencies in vitamin B-2 (riboflavin), B-3 (niacin), vitamin B-6 (pyridoxine), vitamin B-12 (cyanocobalamin) and a defieciency in iron are also among the causes of angular cheilitis.

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