Apocrine Duct Occlusion

Below you will find more information about Apocrine Duct Occlusion from Medigest. If you believe that you are suffering from any of the symptoms of Apocrine Duct Occlusion it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Apocrine Duct Occlusion and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Apocrine Duct Occlusion comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Apocrine duct Occlusion, commonly known as the Fox-Fordyce disease, is an uncommon skin disorder, affecting male and children, but is more common in women between 13 and 35 years old. This condition is characterized by the sudden development of itchy bumps usually around hair follicles of nipples, underarm areas and pubic region.


Diagnosis is made by observing clinical signs of the rash and assessing patient history.


There is no specific cure for Apocrine duct occlusion. However, oral antibiotics, topical steroids, topical retinoids and clindamycin solution may be prescribed to help alleviate the itchiness. Other therapies may include surgical excision, ultraviolet radiation, dermabrasion, liposuction and anti-androgenic hormonal therapy. Some cases clear up during pregnancy or menopause for unknown reasons. However, the disease could persist afterwards.

Symptoms and Signs

Apocrine duct Occlusion starts with an intense itchy that could disrupt sleep. However, some cases are asymptomatic. Common signs include a darkened and thickened dry skin due to persistent scratching, dome-shaped small papules that affect hair follicles in the infected area and an obvious reduce in sweating in the affected area.


The cause of Apocrine duct Occlusion remains unknown. However, it has been associated with rupture of the apocrine sweat ducts, which result in the inflammation and itching of the affected area. Other factors that may play a role in the development of this condition include stress, changes in sweat components, emotional and hormonal influences as well as environmental factors, like humidity, heat and friction.

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