Below you will find more information about Apudoma from Medigest. If you believe that you are suffering from any of the symptoms of Apudoma it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Apudoma and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Apudoma comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


An apudoma is any endocrine tumor that arises from an APUD cell (APUD, meaning amine precursor uptake and decarboxylation) properties. These cells, which are derived from neural crest cells, are from structures such as the prostate, pancreas and ampulla of Vater. First identified in 1975, Apudoma is a very general term. As such, most doctors and scientists prefer to use a more specific term when possible, such as apudoma of gall bladder.

Clinical Features

"Structurally, apudoma tumors often display electron-dense granules, which produce multiple regulatory amines and hormones, chromogranin A or C, synaptophysine and neuron-specific enolase. Amine precursor uptake and decarboxylation cells are known to give rise to islet cell tumors of the pancreas, medullary carcinomas of the thyroid, phaeochromocytomas, melanomas and carcinoid tumors. As such, symptoms and histology of pancreatic islet cell tumors and apudoma have striking similarities. "

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