Autoimmune hepatitis

Below you will find more information about Autoimmune hepatitis from Medigest. If you believe that you are suffering from any of the symptoms of Autoimmune hepatitis it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Autoimmune hepatitis and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Autoimmune hepatitis comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Autoimmune hepatitis is an abnormal presentation of human leukocyte antigen (HLA) class II on the exterior of hepatocytes it might be because of the hereditary predisposition or severe liver infection that results to a cell-mediated immune response in opposition of the body's liver causing autoimmune hepatitis.

Prevalence

Autoimmune hepatitis has an occurrence of 1-2 per 100,000 per year and 15-20/100,000 as prevalence. Like with other diseases it affects mostly women the ration is 8:1. Liver enzymes are augmented like bilirubin. Autoimmune can result to cirrhosis when it progresses.

Diagnosis

Physical exam Liver function tests Antinuclear antibodies (ANA) test Smooth muscle cells (SMA) antibodies Liver/kidney microsomes (anti-LKM) Liver biopsy The diagnosis of autoimmune hepatitis always requires liver biopsy. Scoring system can be used in complicated cases. The best way to achieve the diagnosis is through a combination of laboratory examinations.

Prognosis

Out of 10 people, 7 people affected by this disease go into reduction with the decreasing of the severity of symptoms within tow years of initial treatment. The part where the disease was reduced will reoccur in about 3 years that is why treatment is needed on and off for years or if not for life.

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