Bantu siderosis

Below you will find more information about Bantu siderosis from Medigest. If you believe that you are suffering from any of the symptoms of Bantu siderosis it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Bantu siderosis and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Bantu siderosis comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Bantu siderosis is the overload of iron primarily seen in South African people. It involves unusual iron deposits in the liver. It is said that several African people are liable to an augmented skill to absorb iron. Initially, this was said to be a cause of ungalvanised barrels utilized to keep home-made beer that led to augmented oxidation and augmented levels of iron in the beer. Additional researches show that only those individuals that drink this beer acquires an overload in iron and the same syndrome happened in the people of African descent. Because of this, researchers were led to discover the gene polymorphism in the gene for ferroportin that prompts several individuals of African descent to overload iron.

Prevalence

Bantu siderosis is classified as a "rare disease" according to the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH) which means that it affects not more than 200,000 individuals in the US population.

Symptoms and Signs

Iron deposits in liver Asymptomatic Liver cirrhosis Impaired liver function Liver is enlarged Iron deposits in spleen Iron deposits in bone marrow

Complications

The main complication of Bantu siderosis is liver cancer.

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