Bartter syndrome, classic form

Below you will find more information about Bartter syndrome, classic form from Medigest. If you believe that you are suffering from any of the symptoms of Bartter syndrome, classic form it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Bartter syndrome, classic form and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Bartter syndrome, classic form comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Bartter syndrome, classic form is an unusual hereditary abnormality in the thick ascending limb of the ring of Henle. It is distinguished by decreased potassium levels, low acidity of blood (alkalosis), and regular to decreased blood pressure. 2 types of Barter syndrome: Neonatal Bartter syndrome Classic Bartter syndrome It is closely related to Gitelman syndrome which is milder comparing it to both Bartter syndrome subtypes.


Chronic vomiting Abuse of diuretic medications (water pills) Magnesium deficiency Bartter syndrome can also elevate renin and aldosterone levels on patients.


Angiotensin-converting enzyme Moderate amounts of sodium Moderate amounts of potassium Potassium supplements Spironolactone - to reduce loss of potassium NSAIDs acronym for Nonsteroidal antiinflammatory drugs

Characteristics and Features

Patients that has classic Bartter syndrome can have symptoms in the initial two years of life, though they are commonly diagnosed at school age or later. Patients also have polyuria, polydipsia, and a propensity to dehydration, though usual or just a little enlarged urinary calcium secretion without the propensity to increase kidney stones. Individuals who has this syndrome comprise vomiting and growth delay. Kidney job is also usual if the ailment is cured though irregularly patients continue to end-stage renal failure. Bartter's syndrome comprise of hypokalaemia, alkalosis, normal blood pressures, and high plasma renin and aldosterone. Several causes of this condition almost certainly survive. Methodical indicators comprise of elevated urinary potassium and chloride in spite of small serum values, augmented plasma renin, hyperplasia of the juxtaglomerular equipment on renal biopsy, and cautious elimination of diuretic exploitation. Overindulgence creation of renal prostaglandins is repeatedly starts.

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