Catel Manzke Syndrome

Below you will find more information about Catel Manzke Syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Catel Manzke Syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Catel Manzke Syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Catel Manzke Syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Catel Manzke syndrome is an uncommon genetic disorder combining glossoptosis, cleft palate, and micrognathia with an abnormality of the index fingers. Apart from the major features, there are also several related malformations described, particularly growth retardation and cardiac defect.

Diagnosis

A physician can generally diagnose the condition through physical exam. Checking with a specialist in genetics can help rule out additional problems associated with the syndrome.

Treatment

Treatment will vary depending on a patient's symptoms. Nasopharyngeal cannulation is often done for infants until their jaw grows enough for the tongue to assume a more usual placement in the airwy and mouth. Cleft palate can usually be repaired by a maxillofacial or plastic surgeon. Other treatments may include a language and speech therapy, and physchologist.

Symptoms and Signs

Infants born with the syndrome have symptoms of supernumerary, unevenly shaped bone called Hyperphalangy found between the index finger's first bone and the matching bone within the second carpal. Other symptoms include small lower jaw, cleft palate, growth deficiency, malformed ears, cardiac defects, aortic narrowing, and septal defects.

Causes

Catel Manzke syndrome generally seems to occur at random, for unidentified sporadic reasons. The proposed cause is microdeletion, probably resultant in a closest gene syndrome; however, this may only be proved through ongoing cytogenetic evaluation of other cases using advanced methods.

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