Cerebral amyloid angiopathy

Below you will find more information about Cerebral amyloid angiopathy from Medigest. If you believe that you are suffering from any of the symptoms of Cerebral amyloid angiopathy it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Cerebral amyloid angiopathy and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Cerebral amyloid angiopathy comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Cerebral amyloid angiopathy is a condition that affects the small blood vessels of the brain, wherein the amyloid protein associated with the Alzheimer's disease is deposited in the vessel walls. This may result in brain diseases such as dementia, brain hemorrhage, and stroke. Patients with cerebral amyloid angiopathy are usually older than 65 years old, although it may also occur in those who are around 45 years of age. The disease prevalence increases with age, and equally affects both men and women. Cerebral amyloid angiopathy is responsible for 5-20% of brain hemorrhage occurrences, and 30% of lobar hemorrhage.

Causes

The cause for cerebral amyloid angiopathy may be genetic, but it can also occur sporadically. The condition is hereditary, and chromosome 21 is responsible for the amyloid accumulation that results in the disease. Sporadic cerebral amyloid angiopathy, however, is the more common cause, and it is associated with the aging process. Genetic factors related to acquiring cerebral amyloid angiopathy are: Dutch genes with amyloidosis, Flemish hereditary cerebral hemorrhage, familial Alzheimer's disease, and Down syndrome.

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