Cicatricial pemphigoid

Below you will find more information about Cicatricial pemphigoid from Medigest. If you believe that you are suffering from any of the symptoms of Cicatricial pemphigoid it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Cicatricial pemphigoid and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Cicatricial pemphigoid comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Cicatricial pemphigoid is a comparatively rare blistering disease involving the mucous membranes of the eyes, mouth, throat, nose, and genitals. The disease is an autoimmune disease wherein the immune system generates antibodies that attack certain proteins that attach the epidermal cells to each other. The disrupted connection causes the cell to separate from the skin's lower layers, thus blisters form.

Diagnosis

Doctors typically identify cicatricial pemphigoid through its characteristic blisters, but it is analyzed with certainty by skin sample examination. At times, doctors make use of "special chemical stains" that permit the visibility of antibody deposits under a microscope.

Treatment

The kind of treatment will generally depend on the severity of the disease. Corticosteroids in high dose are often a mainstay treatment. A patient can also go through plasmapheresis, which is a process of filtering antibodies from one's blood. Gold salt injections are sometimes used. Antibiotics may also be needed in treating infections of rupture blisters.

Symptoms and Signs

Some common symptoms of cicatricial pemphigoid include inflamed eyes, red eyes, mucous membrane blistering and scarring, and red swollen mucous membrane.

Causes

Like any other autoimmune disease, environmental factors mixed with genetic vulnerability lead to the growth of autoantibodies that can cause cicatricial pemphigoid.

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