Coproporhyria

Below you will find more information about Coproporhyria from Medigest. If you believe that you are suffering from any of the symptoms of Coproporhyria it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Coproporhyria and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Coproporhyria comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

Coproporhyria, also known as Porphria, is a term used to define a set of hereditary disorders arising from troubles in the body's manufacture of a substance identified as 'heme'. Heme is present in each body tissue. The body utilizes enzymes to transform 'porphyrins' into heme. When one of the enzymes has an inherited deficiency, the process of transformation is interrupted. This causes porphyrins to accumulate in one's body, which in turn leads to the symptoms of Coproporhyria.

Diagnosis

If the doctor suspects Coproporhyria, she or he may recommend tests, including blood test, urine test, and stool sample test.

Treatment

Treatment is aimed at eliminating symptoms, and can include medicines to manage pain, stopping trigger medications, intravenous sugar, intravenous fluids, and hematin. Other treatments include phlebotomy and activated charcoal.

Symptoms and Signs

Symptoms may depend on the severity and type of Coproporhyria. Indications of the disease will include serious abdominal pain, vomiting, constipation, seizures, disorientation, hallucinations, confusion, red urine, paranoia, hypertension, muscle pain, numbness, tingling, paralysis or weakness, and pain in legs, back, or arms. When the disease is cutaneous, symptoms will include skin swelling, itching, blisters, red urine, and painful redness of the skin.

Causes

The condition is inherited. A few types of this disease root from defective genes inherited from parents. Defects in the gene cause enzymes involved in the conversion of porphyrin into heme to become abnormal.

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