Prinzmetal’s Variant Angina

Below you will find more information about Prinzmetal’s Variant Angina from Medigest. If you believe that you are suffering from any of the symptoms of Prinzmetal’s Variant Angina it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Prinzmetal’s Variant Angina and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Prinzmetal’s Variant Angina comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Prinzmetal's variant angina also known as variant angina, Prinzmetal's angina or angina inversa is a syndrome characterized by cardiac chest pain at rest usually when lying in bed, which usually occurs in cycles.


Echocardiography or thallium scintigraphy is used in the aim to diagnose prinzmetal's variant angina. ECG finding will demonstrate elevated ST segment rater than ST depression. Coronary angiography using injections of provocative agents such as ergonovine, acetylcholine or methylergonovine into the coronary artery is the most effective way in the diagnosis of Prinzmetal's variant angina. Once provocative substance is introduced exaggerated spasms are visualized in the image view confirming diagnosis of prinzmetal's variant angina.


Nitrates and calcium channel blocker are typically used in the treatment of Prinzmetal's variant angina.

Symptoms and Signs

Chest pain episodes are usually prominent at rest rather than when engage in activity. Other possible symptoms that come with the syndrome include upper arm pain, shortness of breath, tight chest, and jaw pain. Heart palpitations are present in some cases.


Prinzmetal's variant angina is caused by narrowing of the coronary arteries due to contraction of the smooth muscle tissue in the walls of the blood vessels; however what really caused the contraction is still not yet known.

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