Proconvertin Deficiency, Congenital

Below you will find more information about Proconvertin Deficiency, Congenital from Medigest. If you believe that you are suffering from any of the symptoms of Proconvertin Deficiency, Congenital it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Proconvertin Deficiency, Congenital and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Proconvertin Deficiency, Congenital comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Proconvertin deficiency, congenital also known as Factor VII deficiency is a rare inherited blood disorder caused by insufficiency of Factor VII blood protein, which can lead to poor blood coagulation.


Activated partial thromboplastin time (aPTT) test, Prothrombin time test, and thrombin time test can provide diagnosis of proconvertin deficiency, congenital. Confirming diagnosis is done through factor VII assay.


Prothrombin complex concentrates are used to treat proconvertin deficiency, congenital. Fresh frozen plasma can also be used as part of the treatment plan for patients with proconvertin deficiency, congenital. Bleeding episodes of patients with this disorder can be treated with a recombinant factor VIIa product of Novo Nordisk named Novoseven.

Symptoms and Signs

Proconvertin deficiency, congenital can sometimes be asymptomatic. In other cases, symptoms may present including excessive bleeding in different conditions such as after injury or after tooth extraction. Individuals with proconvertin deficiency, congenital usually experience excessive menstrual bleeding and spontaneous nose bleeding. They tend to get bruises easily and bleeding into joints is common. Internal bleeding may occur in the head, stomach, urinary tract, and intestines.


Proconvertin deficiency, congenital is caused by lack of blood protein called Factor VII, an important clotting protein. The disorder can be inherited in an autosomal recessive pattern of inheritance.

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