Raine Syndrome

Below you will find more information about Raine Syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Raine Syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Raine Syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Raine Syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Raine syndrome is a rare disease in newborn infants characterized by intracranial calcification, or an abnormal increase in bone density, which can prove ultimately fatal. Raine syndrome is also alternatively called osteosclerotic bone dysplasia.

Symptoms and Signs

Raine syndrome presents with craniofacial anomalies, including exophthalmos, midface hypoplasia, microcephaly, cleft palate, gum hypertrophy and generalized osteosclerosis on radiography in newborns. Infants born with this condition usually die within a few hours after birth.

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