Romano-Ward Syndrome

Below you will find more information about Romano-Ward Syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Romano-Ward Syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Romano-Ward Syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Romano-Ward Syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Romano-Ward syndrome is a major variant of a heart condition known as long QT syndrome, a condition that causes the cardiac muscle to take abnormally longer to recharge between beats. Romano-Ward syndrome is characterized by a disruption of the heart's normal rhythm.

Symptoms and Signs

Romano-Ward syndrome is the most common type of hereditary long QT syndrome, which occurs in approximately 1 in 5,000 individuals worldwide. However, it is believed that more people are afflicted but never show symptoms of the disease. The hallmark sign of Romano-Ward syndrome is irregular heartbeats. If untreated, this can lead to seizures, fainting, or sudden death.


Romano-Ward syndrome is a hereditary disease, passed on via autosomal dominant pattern. The condition can develop as a consequence of mutations in the following genes: KCNE1, ANK2, KCNH2, KCNE2, KCNQ1, and SCN5A.

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