Schmidt Syndrome

Below you will find more information about Schmidt Syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Schmidt Syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Schmidt Syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Schmidt Syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Schmidt syndrome is an adrenal defect that commonly occurs with another glandular disorder. Schmidt syndrome is also known as "autoimmune polyendocrine syndrome type 2", a more heterogeneous form of autoimmune polyendocrine syndrome which affects one or more endocrine organs but has also been known to invade other non-endocrine organs. Schmidt syndrome is a more commonly occurring type of autoimmune polyendocrine syndrome.

Symptoms and Signs

Schmidt syndrome typically manifests with hypothyroidism, diabetes mellitus type 1, and Addison's disease. Less common manifestations include vitiligo and hypogonadism.


Schmidt syndrome has not been linked to a specific gene. However, certain genetic risk factors have been identified; in particular, carriers of a certain HLA genotype seem to be predisposed to the disease.

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