Sezary’s lymphoma

Below you will find more information about Sezary’s lymphoma from Medigest. If you believe that you are suffering from any of the symptoms of Sezary’s lymphoma it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Sezary’s lymphoma and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Sezary’s lymphoma comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Sezary's lymphoma is a type of cutaneous lymphoma that usually starts in or on the skin. The cancer is marked by the excessive propagation of T-cells which are a type of white blood cell. The extent of skin involvement is uneven and most of the time patchy.


A blood test will be ordered by the physician if there are suspicions of Sezary's lymphoma on a characteristic skin lesion that does not heal with normal medication. A skin biopsy is also carried out to confirm diagnosis and prevent incidents of misdiagnosis.


Chemotherapy, radiation therapy and photodynamic therapy are used in combination with medications with the aim to help control the spread of the cancer.

Symptoms and Signs

Symptoms of Sezary's lymphoma primarily appear on the skin at the onset of the disease. This may include some of the following: ò Widespread erythroderma which is characterized by reddening or scaling of the skin almost covering the entirety of the skin. But there are also cases, wherein reddening or scaling only appears in patches. ò Disease of the lymph nodes which is often presented by swollen, enlarged or inflamed lymph nodes. ò Presence of nonconforming and strange T-cells in the peripheral blood. ò Enlargement of the liver corresponding with enlargement of the spleen (hepatosplenomegaly).


There is still no definite proof establishing what really causes Sezary's lymphoma.

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