Sipple Syndrome

Below you will find more information about Sipple Syndrome from Medigest. If you believe that you are suffering from any of the symptoms of Sipple Syndrome it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Sipple Syndrome and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Sipple Syndrome comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Sipple syndrome is a group of rare inherited disorders that causes the growth of tumors in several glands. It is also known as Multiple Endocrine Neoplasia Type 2. Tumors produced by this syndrome can either be benign or malignant. Sipple syndrome is a subtype of multiple endocrine Neoplasia producing tumors that generally occur in endocrine glands and sometimes in endocrine tissues.


Careful evaluation of the symptoms and underlying medical condition like the presence of tumors may lead to the diagnosis of Sipple syndrome. Specific diagnostic procedures may be carried out to confirm the diagnosis. The use of CT scan and MRI may lead to discovery of tumors developing in multiple glands.


Treatment for Sipple syndrome is aimed at eliminating the tumors. Subsequent therapy should be carried out to prevent or minimized the remaining symptoms while hormone replacement therapy may be necessary when glands are surgically removed and hormone secretion is not enough.

Symptoms and Signs

Signs and symptoms of Sipple syndrome include the following: ò Pain in the abdominal region ò Abdominal distension ò Loss of appetite ò Uneasiness ò Nausea ò Excessive urination ò Dehydration ò Rapid heart beat ò Irritability ò Paleness ò Nervousness ò Tremors ò Excessive sweating ò Increased blood pressure (hypertension) ò Increased blood calcium level ò Thyroid tumor


Most cases of Sipple syndrome are pointed to result from autosomal dominant inheritance. It is rare in children and may occur any time from adolescence to old age.

Discuss Sipple Syndrome in our forums

Discuss Sipple Syndrome with other members of Medigest in our forums.