Strumpell-lorrain Disease

Below you will find more information about Strumpell-lorrain Disease from Medigest. If you believe that you are suffering from any of the symptoms of Strumpell-lorrain Disease it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Strumpell-lorrain Disease and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Strumpell-lorrain Disease comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


The common feature of these syndromes is progressive, often severe, spasticity in the lower extremities of the patient's body. Hereditary spastic paraplegia (HSP) is also known as familial spastic paraparesis and Strumpell-Lorrain syndrome. A number of clinical reports have documented that HSP syndromes are heterogeneous. Syndromes are categorized as uncomplicated or pure when only spinal involvement occurs, and they are classified as complicated when they are associated with neurologic abnormalities such as ataxia, mental retardation, dementia, extrapyramidal dysfunctions, visual or hearing dysfunctions, adrenal insufficiency, and ichthyosis. Inheritance of the disease may be X-linked, autosomal recessive, or autosomal dominant. The most useful classifications now are based on inheritance and genetic linkage. Clinical distinctions between pure and complicated forms of HSP have some utility; however, age of onset usually has no clear relation to the HSP genotype.

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