Vas Deferens

Below you will find more information about Vas Deferens from Medigest. If you believe that you are suffering from any of the symptoms of Vas Deferens it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Vas Deferens and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Vas Deferens comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Congenital absence of the vas deferens (CAVD) or congenital bilateral aplasia of vas deferens is a condition in which both vas deferens, fail to form properly prior to birth.

Symptoms and Signs

Men who are missing both vas deferens suffer from a condition known as azzospermia. Meaning, they are able to create sperm but are unable to transport them appropriately; and their semen do not contain any sperm.


Congenital bilateral aplasia of vas deferens is associated with cystic fibrosis and occurs because of a mutation in the CFTR gene. The mutation results in obstructive azoospermia in postpubretal males with cystic fibrosis. CAVD is also one of the most consistent features of cystic fibrosis as it affects 98-99% of individuals in the CF patient population. Acute or persistent respiratory symptoms in contrast are present in only 51% total CF patients.

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