Vasculitis Hypersensitivity

Below you will find more information about Vasculitis Hypersensitivity from Medigest. If you believe that you are suffering from any of the symptoms of Vasculitis Hypersensitivity it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Vasculitis Hypersensitivity and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Vasculitis Hypersensitivity comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

A condition characterized by a reaction that results in the inflammation of the blood vessels, hypersensitivity vasculitis happens when immune complexes lodge in the vessel wall, attracting polymorphonuclear leukocytes that in turn release tissue-degrading substances leading to an inflammatory process.

Diagnosis

Henoch-Schonlein purpura is an important differential in diagnosing hypersensitivity vasculitis. Among the criteria are ages 16 above, use of possible triggering drugs, palpable painful purpura, maculopapular rash, and skin biopsy showing neutrophil infiltration.

Treatment

Eliminating the cause of vasculitis is the most important part of the treatment. Some patients find taking antihistamines useful. Immunosuppressive agents are suggested if the vasculitis is damaging systems such as the kidneys.

Symptoms and Signs

Normally painful and palpable petechiae or purpura is the common symptom of the condition. The purpura or skin vasculitis normally arise on crops, with common localizations on the forearms and legs. Lesions with black or brown centres usually result from necrosis of skin. The disorder sometimes affects nerves, the kidneys, joints and the heart. Also common is renal involvement.

Causes

The disorder is usually due to a hypersensitivity reaction to a known drug, auto-antigens or infectious agents such as bacteria.

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