Willebrand Disease

Below you will find more information about Willebrand Disease from Medigest. If you believe that you are suffering from any of the symptoms of Willebrand Disease it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Willebrand Disease and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Willebrand Disease comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Von Willebrand disease or VWD for brevity, is an inherited bleeding disorder which affects the body's ability to clot open wounds which causes heavy and continuous bleeding.


Diagnosis includes examination of medical history of patients, physical examinations for unusual bruises and bleeding, blood tests and other tests like the Von Willebrand factor antigen, ristocetin, mutimer and platelet function tests are used to confirmed the disease.(Sadler, J. E. (1998) "Biochemistry and Genetics of von Willebrand factor." Annu Rev Biochem; 67:395-424).


Treatment includes adminsitration of Desmopressin which is usually injected or nasal spray, administration of birth pills to decrease menstrual blood loss. Other physicians also advised aminocaproic acid or tranexamic acid which is antifibrinolytic drug that can reduce bleeding.

Symptoms and Signs

Its symptoms includes large bruising or injuries, frequent or hard to stop nosebleeds, long bleeding of the gums after a dental procedure, blood in the stool, heavy mentrual period in women and in giving birth, unusual and heavy bleeding after a cut or after surgical operation.


Von Willebrand disease is an inherited disease..

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