Yolk Sac Tumor

Below you will find more information about Yolk Sac Tumor from Medigest. If you believe that you are suffering from any of the symptoms of Yolk Sac Tumor it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with Yolk Sac Tumor and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to Yolk Sac Tumor comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.


Yolk sac tumor, YST for brevity, and which is otherwise known as the Endodermal sinus tumor or the infantile embryonal carcinoma, is a type of germ cell tumor group of cancers and is said to be common to children under three years old.


Diagnosis includes biopsy and AFT test results for EST. Furthermore, a GATA-4 or transcription factor is also used to confirm the disease (Siltanen S, Anttonen M, HeikkilΣ P, Narita N, Laitinen M, Ritvos O, Wilson DB, Heikinheimo M (1999). "Transcription factor GATA-4 is expressed in pediatric yolk sac tumors.". Am. J. Pathol. 155 (6): 1823-9).


Treatments includes surgery and chemotherapy.

Symptoms and Signs

Symptoms includes the occurrence of a benign but malignant endodermal sinus tumor.


It is usually cause by a malignant endodermal cells which express alpha-fetoprotein.

Discuss Yolk Sac Tumor in our forums

Discuss Yolk Sac Tumor with other members of Medigest in our forums.