ZAP70 Deficiency

Below you will find more information about ZAP70 Deficiency from Medigest. If you believe that you are suffering from any of the symptoms of ZAP70 Deficiency it is important that you obtain an accurate diagnosis from a medical professional to ensure that you obtain the correct medication or treatment for your condition. There are medical conditions that carry similar symptoms associated with ZAP70 Deficiency and therefore the information provided by Medigest is offered as a guideline only and should never be used in preference to seeking professional medical advice. The information relating to ZAP70 Deficiency comes from a third party source and Medigest will not be held liable for any inaccuracies relating to the information shown.

Definition

ZAP70 deficiency, the short term used for zeta-chain-associated protein 70 kD deficiency, is a rare and severe combined immunodeficiency.

Treatment

ZAP70 deficiency genetically inherited. It cannot be cured but gene therapy proposed.

Causes

The deficiency is due to a lack of CD8+ T cells and the presence of circulating CD4+ T cells that are unresponsive to T-cell receptor-mediated stimuli.

Discuss ZAP70 Deficiency in our forums

Discuss ZAP70 Deficiency with other members of Medigest in our forums.